Dermatolojide Spektrofotometrik İntrakutanoz Analiz (SIASCOPY) Cihazı ve Kullanım Alanları
Özet
Siaskopi (SIAscopy), deri lezyonlarını 2 mm derinliğe kadar non-invaziv bir şekilde analiz eden, hemoglobin, melanin ve kollajen dağılımı hakkında detaylı bilgiler sunan bir görüntüleme yöntemidir. Cihaz, ışığın farklı dalga boylarını kullanarak elde ettiği verileri "SIAgraf" adı verilen parametrik haritalara dönüştürür ve özellikle melanoma gibi deri kanserlerinin erken tanısında hekimlere objektif bir karar desteği sağlar. Geleneksel dermoskopiden farklı olarak derin doku bileşenlerini de görselleştirebilen bu teknoloji, pigmentasyon bozukluklarının takibinde, yara iyileşmesinin değerlendirilmesinde ve kozmetik ürünlerin etkinliğinin ölçülmesinde de aktif olarak kullanılmaktadır.
SIAscopy is a non-invasive imaging method that analyzes skin lesions up to 2 mm deep, providing detailed information on the distribution of hemoglobin, melanin, and collagen. By utilizing different wavelengths of light, the device transforms data into parametric maps called "SIAgraphs," offering objective decision support for clinicians, particularly in the early diagnosis of melanoma. Distinguishing itself from traditional dermoscopy by visualizing deeper tissue components, this technology is also actively used in monitoring pigmentation disorders, evaluating wound healing, and measuring the efficacy of cosmetic products.
Referanslar
Bhat Y, Zeerak S, Hassan I. The global scenario of melanoma. Pigment Int. 2017;4(2):85.
Jalil B. Multispectral Image Processing Applied to Dermatology. GradvibotU-BourgogneFr [Internet]. 2008; Available from: http://gradvibot.u-bourgogne.fr/thesis1/Jalil_Bushra.pdf
PATEL JK, KONDA S, PEREZ OA, AMINI S, ELGART G BB. Newer technologies/techniques and tools in the diagnosis of melanoma. Eur J Dermatology. 2008;18(6):617–31.
N N-P. Diagnosis and treatment of premalignant changes of photodamaged skin: Novel hyperspectral imaging and new therapeutical aspects. 2015;
Kupetsky EA, Ferris LK. The diagnostic evaluation of MelaFind multi-spectral objective computer vision system. Expert Opin Med Diagn. 2013;7(4):405–11.
Stimpfle DW, Serra AL, Wüthrich RP, French LE, Braun RP, Hofbauer GFL. Spectophotometric intracutaneous analysis: An investigation on photodamaged skin of immunocompromised patients. J Eur Acad Dermatology Venereol. 2015;29(6):1141–7.
Matts PJ CS. Skin care products. 3rd edn. Barel AO, Paye M MH, editor. Handbook of Cosmetic Science and Technology, Third Edition. 2009. 121–134 p.
Terstappen K, Suurküla M, Hallberg H, Ericson MB, Wennberg A-M. Poor correlation between spectrophotometric intracutaneous analysis and histopathology in melanoma and nonmelanoma lesions. J Biomed Opt. 2013;18(6):061223.
Swearingen JA, Holan SH, Feldman MM, Viator JA. Photoacoustic discrimination of vascular and pigmented lesions using classical and Bayesian methods. J Biomed Opt. 2010;15(1):016019.
Sgouros D, Lallas A, Julian Y, Rigopoulos D, Zalaudek I, Longo C, et al. Assessment of SIAscopy in the triage of suspicious skin tumours. Ski Res Technol. 2014;20(4):440–4.
Sakalauskienė K, Valiukevičienė S, Raišutis R, Linkevičiūtė G. The significance of spectrophotometric image analysis for diagnosis of the melanocytic skin tumours in association with their thickness. Ski Res Technol. 2018;24(4):692–8.
D’Alessandro B, Dhawan AP. 3-D volume reconstruction of skin lesions for melanin and blood volume estimation and lesion severity analysis. IEEE Trans Med Imaging. 2012;31(11):2083–92.
Walter FM, Morris HC, Humphrys E, Hall PN, Kinmonth AL, Prevost AT, et al. Protocol for the MoleMateTM UK trial: A randomised controlled trial of the MoleMate system in the management of pigmented skin lesions in primary care [ISRCTN 79932379]. BMC Fam Pract. 2010;11.
Novaković L, Cotton S, Hawk JLM. Spectrophotometric intracutaneous analysis as an early non-invasive predictor of efficacy in the phototherapy of psoriasis. Photodermatol Photoimmunol Photomed. 2009;25(2):81–5.
Haniffa MA, Lloyd JJ, Lawrence CM. The use of a spectrophotometric intracutaneous analysis device in the real-time diagnosis of melanoma in the setting of a melanoma screening clinic. Br J Dermatol. 2007;156(6):1350–2.
Princevs E, Derveniece A, Hartmane I, Mikazans I, Cema I PO. Combined Method of Imaging with 20 MHz Ultrasound, Spectrophotometric Intracutaneous Analysis and Pathohistology in Determination of Malignancy Characteristics of Basal Cell Skin Cancer – Review of Literature. Medical Basics Sciences. 2012. 171–183 p.
Avanaki MRN, Hojjat A, Podoleanu AG. Investigation of computer-based skin cancer detection using optical coherence tomography. J Mod Opt. 2009;56(13):1536–44.
Claridge E, Cotton S, Moncrieff M, Hall P. Spectrophotometric Intracutaneous Imaging (SIAscopy). Handb Non-Invasive Methods Ski Second Ed. 2006;(September):315–25.
Rigel DS, Russak J, Friedman R. The Evolution of Melanoma Diagnosis: 25 Years Beyond the ABCDs. CA Cancer J Clin. 2010;60(5):301–16.
Moncrieff M, Otton S, Claridge E, Hall P. Spectrophotometric intracutaneous analysis: A new technique for imaging pigmented skin lesions. Br J Dermatol. 2002;146(3):448–57.
Satheesha T, Narayana S, Giriprasad M. Review on Early Detection of Melanoma in Situ. IjaterCom [Internet]. 2012;2(4). Available from: http://www.ijater.com/Files/7afc6229-da1c-4853-b89e-5dfda0c6265d_NCET_01_15.pdf
Özdemir F. Melanom Tanısı Diagnosis of Melanoma. Türkderm [Internet]. 2007;41(Özel Sayı 2):6–14. Available from: https://www.journalagent.com/turkderm/pdfs/TURKDERM_41_SUP_2_6_14.pdf
Matts PJ, Dykes PJ, Marks R. The distribution of melanin in skin determined in vivo. Br J Dermatol. 2007;156(4):620–8.
Morse R, Cotton S CM. A new method for simulating the visual effects of haemoglobin and melanin changes within the skin. J Am Acad Dermatol. 2007;56(2):AB98.
Matts PJ, Fink B, Grammer K, Burquest M. Color homogeneity and visual perception of age, health, and attractiveness of female facial skin. J Am Acad Dermatol. 2007;57(6):977–84.
Voigt H, Classen R. Computer vision and digital imaging technology in melanoma detection. Semin Oncol. 2002;29(4):308–27.
Pratavieira S, Andrade CTd, Salvio AG, Bagnato VS KC. Optical imaging as auxiliary tool in skin cancer diagnosis. In: skin cancers — risk factors Prev Ther: InTech. 2011. p. 159–71.
Surgery R, Hospital A, Powell J, Moncrieff M, Hall P. A Comparison Between Dermatoscopy and Spectrophotometric Intracutaneous Analysis ( SIAscopy ) for the Diagnosis of Melanoma. 2002;44(Creagan 1997):1995–6.
Horsch A. Melanoma Diagnosis. In: Biological and Medical Physics, Biomedical Engineering. 2010. p. 307–28.
J.D. E, J. H, P.N. H, A.J. W, M. M, F.M. W. Accuracy of SIAscopy for pigmented skin lesions encountered in primary care: Development and validation of a new diagnostic algorithm. BMC Dermatol [Internet]. 2010;10(9). Available from: http://www.embase.com/search/results?subaction=viewrecord&from=export&id=L51088555%5Cnhttp://www.biomedcentral.com/1471-5945/10/9%5Cnhttp://dx.doi.org/10.1186/1471-5945-10-9%5Cnhttp://sfx.library.uu.nl/utrecht?sid=EMBASE&issn=14715945&id=doi:10.1186%2F147
Vasefi F, MacKinnon N, Saager R, Durkin AJ, Chave R, Farkas DL. Quantifying the optical properties of turbid media using polarization sensitive hyperspectral imaging (SkinSpect): two-layer optical phantom studies. Imaging, Manip Anal Biomol Cells, Tissues XIII. 2015;9328:93280A.
Tehrani H, Walls J, Morse R CS. The In-Vivo Image Analysis of Tumour Vasculature in the Diagnosis of Non-Melanoma Skin Cancer. Am Acad Dermatology. 2006;
Terushkin V, Halpern AC. Melanoma Early Detection. Hematol Oncol Clin North Am [Internet]. 2009;23(3):481–500. Available from: http://dx.doi.org/10.1016/j.hoc.2009.03.001
Ferris LK, Harris RJ. New Diagnostic Aids for Melanoma. Dermatol Clin [Internet]. 2012;30(3):535–45. Available from: http://dx.doi.org/10.1016/j.det.2012.04.012
Hunter, J, and Moncrieff, M et al. Diagnostic characteristics of SIAscopy versus dermoscopy for pigmented skin lesions presenting in primary care. Br J Dermatol. 2006;155:47–8.
A. W, H. M, J. E, P.N. H, S. C, A.T. P, et al. Evaluation of the MoleMateTM training program for assessment of suspicious pigmented lesions in primary care. Inform Prim Care [Internet]. 2008;16(1):41–50. Available from: http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=emed8&NEWS=N&AN=2008294263
Kimball AB, Kaczvinsky JR, Li J, Robinson LR, Matts PJ, Berge CA, et al. Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: Results of a randomized, double-blind, vehicle-controlled trial. Br J Dermatol. 2010;162(2):435–41.
Ortonne J-P, Sharma V, Verschoore M, Gupta S. Determination of melanin and haemoglobin in the skin of idiopathic cutaneous hyperchromia of the orbital region (ICHOR): A study of Indian patients. J Cutan Aesthet Surg. 2012;5(3):176.
Makhecha M, Nagzarkar R, Khatib Y, Khade A. A comparative study of the efficacy of 2% Hydroquinone, 2% Kojic acid and 30% Glycolic peel in the treatment of Facial Melasma and evaluation of melanin content using SIAscopy-A novel objective method of assessment. Sch J Appl Med Sci [Internet]. 2016;4(iib):3948–53. Available from: http://saspublisher.com/sjams/
Barysch MJ, Rümmelein B, Kolm I, Karpova MB, Schönewolf N, Bogdan Allemann I, et al. Split-face study of melasma patients treated with non-ablative fractionated photothermolysis (1540 nm). J Eur Acad Dermatology Venereol. 2012;26(4):423–30.
Hawkins S CB. Clinical improvement with 12-hydroxystearic acid: A cosmetic PPAR lipid for skin lightening benefits in photodamaged arms. J Am Acad Dermatol. 2013;68(4):AB184.
Rutkowski D, Syed F, Matthews LC, Ray DW, McGrouther DA, Watson REB, et al. An abnormality in glucocorticoid receptor expression differentiates steroid responders from nonresponders in keloid disease. Br J Dermatol. 2015;173(3):690–700.
Ud-Din S, Thomas G, Morris J, Bayat A. Photodynamic therapy: An innovative approach to the treatment of keloid disease evaluated using subjective and objective non-invasive tools. Arch Dermatol Res. 2013;305(3):205–14.
Ud-Din S, Perry D, Giddings P, Colthurst J, Zaman K, Cotton S, et al. Electrical stimulation increases blood flow and haemoglobin levels in acute cutaneous wounds without affecting wound closure time: Evidenced by non-invasive assessment of temporal biopsy wounds in human volunteers. Exp Dermatol. 2012;21(10):758–64.
Perry D, Colthurst J, Giddings P, McGrouther DA, Morris J, Bayat A. Treatment of symptomatic abnormal skin scars with electrical stimulation. J Wound Care. 2010;19(10):447–53.
Perry DM, McGrouther DA, Bayat A. Current tools for noninvasive objective assessment of skin scars. Plast Reconstr Surg. 2010;126(3):912–23.
Murison M JW. Preliminary evaluation of the efficacy of Dermatix silicone gel in the reduction of scar elevation and pigmentation. J Plast Reconstr Aesthetic Surg. 2006;59(4):437–9.
Tehrani H, Moncrieff M, Philp B DP. Spectrophotometric Intracutaneous Analysis. Ann Plast Surg. 2008;61(4):437–40.
Callaghan TM, Wilhelm KP. A review of ageing and an examination of clinical methods in the assessment of ageing skin. Part 2: Clinical perspectives and clinical methods in the evaluation of ageing skin. Int J Cosmet Sci. 2008;30(5):323–32.
Vaitkuviene A, Vaitkus J. World laserology congress. Laser Ther. 2013;22(4):290–2.
