Geriatrik Özen: Eşlik Eden Psikiyatrik Hastalıklar ve Diğerleri

Yazarlar

Abdullah Burak Uygur

Özet

65 yaş ve üzeri geriatrik popülasyonda eşlik eden psikiyatrik hastalıkların (eş tanı) tanı ve tedavi süreçlerini inceleyen metinde, yaşlılık dönemindeki ruh sağlığı değişimlerinin normal yaşlanmanın bir parçası sayılarak göz ardı edildiği ve bu durumun tanı süreçlerini karmaşıklaştırarak daha yoğun tedaviler gerektirdiği belirtilmektedir. Yaşlılarda ilaç kullanımının fazla olması sebebiyle yeni belirtilerin ilaç yan etkisi ya da hiponatremi gibi klinik sorunlar olabileceği unutulmamalı ve tedavilere düşük dozla başlanmalıdır. Geriatrik depresyon gençlere kıyasla daha az depresif duygudurum, daha fazla ilgisizlik ve somatik yakınmalarla seyrederken; yalnız yaşama ve kronik hastalıklar gibi risk faktörleriyle tetiklenmektedir. Tedavide Seçici Serotonin Geri Alım İnhibitörleri (SSRI) ilk sırada yer almakta, uygun hastalarda psikoterapiler de etkili olmaktadır. Yaşlılarda anksiyete sıklıkla nörolojik ve kardiyovasküler hastalıklarla birlikte görülmekte ve düşme korkusu gibi durumlar agorafobi ile karıştırılabilmektedir. Benzodiazepin kullanımı bağımlılık riski nedeniyle 2-4 hafta ile sınırlandırılmalı ve kademeli olarak azaltılmalıdır. Yaşlılıkta psikoza yol açan nedenler birincil ve ikincil olarak ikiye ayrılmakta, deliryum ve demans gibi ikincil nedenlerin öncelikle dışlanması gerekmektedir. Son olarak, yoğun bakım ünitelerinde yatan geriatrik hastalarda depresyon, anksiyete ve TSSB gibi psikiyatrik eş tanıların genel popülasyona göre anlamlı derecede yüksek olduğu ve bu durumun erken tarama ile tedavi edilmesinin önemi vurgulanmaktadır.

This study investigates the diagnosis and treatment processes of concomitant psychiatric disorders (comorbidity) in the geriatric population aged 65 and older, noting that mental health changes in late life are often overlooked as a normal part of aging, which complicates diagnostic processes and requires more intensive treatments. Due to polypharmacy in the elderly, it must be considered that new symptoms could be drug side effects or clinical issues like hyponatremia, and treatments should be initiated at low doses. Geriatric depression presents with less depressive mood and more apathy and somatic complaints compared to younger individuals, and it is triggered by risk factors such as living alone and chronic illnesses. Selective Serotonin Reuptake Inhibitors (SSRIs) are the first-line choice in treatment, and psychotherapies are also effective in suitable patients. Anxiety in the elderly frequently co-occurs with neurological and cardiovascular diseases, and conditions like fear of falling can be confused with agoraphobia. Benzodiazepine use should be limited to 2–4 weeks due to the risk of dependence and must be tapered gradually. Causes leading to psychosis in old age are divided into primary and secondary, and secondary causes such as delirium and dementia must be ruled out first. Lastly, it is highlighted that the prevalence of psychiatric comorbidities such as depression, anxiety, and PTSD is significantly higher in geriatric patients hospitalized in intensive care units compared to the general population, emphasizing the importance of early screening and treatment.

Referanslar

Abla Mehio S, Aline S, Jiana T. Ageing and health in the Arab region: challenges, opportunities and the way forward. Popul Horizons. 2017;14(2):73-84.

Elixhauser A, Steiner C, Harris DR, ve ark. Comorbidity Measures for Use with Administrative Data Medical Care. 1998;36(1):8-27.

El-Gilany AH, Elkhawaga GO, Sarraf BB. Depression and its associated factors among elderly: a community-based study in Egypt. Arch Gerontol Geriatr. 2018;77:103-107.

Karam G, Itani L, Fayyad J, ve ark. Prevalence, Correlates, and Treatment of Mental Disorders among Lebanese Older Adults: A National Study. Am J Geriatr Psychiatry. 2016;24(4):278-286.

Ghaddar A, Fawaz M, Khazen G. Prevalence of depression in Parkinson's disease in a Lebanese tertiary clinic. J Clin Exp Neuropsychol. 2016;38(1):51-58.

Bowirrat A, Oscar-Berman M, Logroscino G. Association of depression with Alzheimer's disease and vascular dementia in an elderly Arab population of Wadi-Ara, Israel. Int J Geriatr Psychiatry. 2006;21(3):246-251.

Ahmed D, El Shair IH, Taher E. Prevalence and predictors of depression and anxiety among the elderly population living in geriatric homes in Cairo, Egypt. J Egypt Public Health Assoc. 2014;89(3):127-135

Hallit S, Daher MC, Hallit R. Correlates associated with mental health and nutritional status in Lebanese older adults: a cross-sectional study. Arch Gerontol Geriatr. 2020;87

El Kady HM, Ibrahim HK. Depression among a group of elders in Alexandria, Egypt. East Mediterr Health J. 2013;19(2):167-174.

Krishnan KR, Hays JC, Tupler LA, ve ark. Clinical and phenomenological comparisons of late-onset and early-onset depression. Am J Psychiatry. 1995;152:785-788.

Brodaty H, Luscombe G, Parker G, ve ark. Early and late onset depression in old age: different aetiologies, same phenomenology. J Affect Disord. 2001;66:225-236.

Kalayam B, Alexopoulos GS. Prefrontal dysfunction and treatment response in geriatric depression. Arch Gen Psychiatry. 1999;56:713-718.

Brown PJ, Roose SP, Zhang J, ve ark. Inflammation, depression, and slow gait: a high mortality phenotype in later life. J Gerontol A Biol Sci Med Sci. 2016;71:221-227.

Fried LP, Tangen CM, Walston J, ve ark. Cardiovascular Health Study Collaborative Research Group. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56:146-156.

Mezuk B, Lohman M, Dumenci L, ve ark. Are depression and frailty overlapping syndromes in mid- and late-life? A latent variable analysis. Am J Geriatr Psychiatry. 2013;21:560-569.

Brown PJ, Roose SP, Fieo R, ve ark. Frailty and depression in older adults: a high-risk clinical population. Am J Geriatr Psychiatry. 2014;22:1083-1095.

Fann WE. Pharmacotherapy in older depressed patients. J Gerontol. 1976;31:304-310.

American Psychiatric Association, Diagnostic and statistical manual of mental disorders (DSM-5). Washington DC. American Psychiatric Publishing. 2013.

Brendel RW, Stern TA. Psychotic symptoms in the elderly. J Clinic Psychiatry 2005; 7: 238-241.

Reinhardt MM, Cohen CI. Late-life psychosis: diagnosis and treatment. Curr Psychiatry Rep 2015; 17: 1.

Cohen CI, Vahia I, Reyes P, ve ark. Schizophrenia in later life: clinical symptoms and well being. Psychiatr Serv 2008; 59: 232-4.

Howard R, Rabins PV, Seeman MV, ve ark. Late onset schizophrenia and very late onset schizophrenia-like psychosis: an international consensus. Am J Psychiatr 2000; 157: 172-8.

Nikayin S, Rabiee A, Hashem MD, ve ark. Anxiety symptoms in survivors of critical illness: a systematic review and meta-analysis. Gen Hosp Psychiatry 2016;43:23-29.

Rabiee A, Nikayin S, Hashem MD, ve ark. Depressive Symptoms After Critical Illness: A Systematic Review and Meta-Analysis. Crit Care Med 2016;44:1744-1753.

Parker AM, Sricharoenchai T, Raparla S, ve ark. Posttraumatic stress disorder in critical illness survivors: a metaanalysis. Crit Care Med. 2015;43:1121-1129.

Wang S, Mosher C, Perkins AJ, ve ark. Post-Intensive Care Unit Psychiatric Comorbidity and Quality of Life. J Hosp Med. 2017;12(10):831-835.

Bienvenu OJ, Colantuoni E, Mendez-Tellez PA ve ark. Co-occurrence of and remission from general anxiety, depression, and posttraumatic stress disorder symptoms after acute lung injury: a 2-year longitudinal study. Crit Care Med 2015;43:642-653.

Wolters AE, Peelen LM, Welling MC, ve ark. Long-Term Mental Health Problems After Delirium in the ICU. Crit Care Med. 2016;44:1808-1813.

Kessler RC, Chiu WT, Demler O, ve ark. Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry 2005;62:617-627.

Mehlhorn J, Freytag A, Schmidt K, ve ark. Rehabilitation interventions for postintensive care syndrome: a systematic review. Crit Care Med 2014;42:1263-1271.

Gelecek

31 Ocak 2022

Lisans

Lisans