Kapsül Endoskopi
Özet
Kapsül endoskopi, gastrointestinal sistemin görüntülenmesi amacıyla kullanılan, minimal invaziv bir tanı yöntemidir. İlk kez 1999 yılında gerçekleştirilen bu işlem, özellikle geleneksel endoskopik yöntemlerin sonuçsuz kaldığı durumlarda, ince bağırsak lümenindeki gizli kanama kaynaklarının, Crohn hastalığının, çölyak hastalığının ve polipozis sendromlarının teşhisinde yüksek başarı oranına sahiptir. İşlem süreci, hastanın sensör kemeri takması ve yaklaşık 1,1 x 1,6 cm boyutlarındaki hap kamerasını yutmasıyla başlar; bu cihaz saniyede 2 ila 35 görüntü kaydederek verileri harici bir alıcıya aktarır. Hazırlık aşamasında hastaların 10-12 saat aç kalması ve gerektiğinde bağırsak temizliği yapması beklenirken, işlem sedasyon gerektirmez ve hasta normal aktivitelerine kısa sürede dönebilir. Kapsül endoskopinin en önemli sınırlılığı biyopsi veya tedavi yapma kabiliyetinin olmamasıdır; ayrıca yutma bozukluğu olanlar, hamileler ve bağırsak darlığı bulunan hastalar için kontrendikasyonlar mevcuttur. Komplikasyon olarak %1-2 oranında kapsül retansiyonu (takılması) görülebilse de, sunduğu yüksek çözünürlüklü görüntüleme kapasitesi ve hasta konforu sayesinde modern gastroenterolojide kritik bir öneme sahiptir.
Capsule endoscopy is a minimally invasive diagnostic method used to visualize the gastrointestinal tract by utilizing a pill-sized camera. First performed in 1999, this procedure has high success rates in diagnosing hidden bleeding sources in the small intestinal lumen, Crohn's disease, celiac disease, and polyposis syndromes, especially when traditional endoscopic methods yield no results. The process begins with the patient wearing a sensor belt and swallowing a capsule camera approximately 1.1 x 1.6 cm in size, which records 2 to 35 images per second and transmits the data to an external receiver. During the preparation phase, patients are expected to fast for 10-12 hours and undergo bowel cleansing if necessary; the procedure requires no sedation, allowing patients to return to their normal activities quickly. The most significant limitation of capsule endoscopy is its inability to perform biopsies or therapeutic interventions; additionally, there are contraindications for patients with swallowing disorders, pregnant women, and those with intestinal strictures. Although capsule retention occurs in approximately 1-2% of cases as a complication, it holds a critical position in modern gastroenterology due to its high-resolution imaging capacity and patient comfort.
Referanslar
Beg S, Parra-Blanco A, Ragunath K. Optimising the performance and interpretation of small bowel capsule endoscopy. Frontline Gastroenterol. 2018; 4:300-308.
Nakajima F, Furumatsu Y, Yurugi T, et al. Investigation of small intestinal lesions in dialysis patients using capsule endoscopy. Hemodial Int. 2019; 23(1):77-80.
Trigo Salado C, Leo Carnerero E, de la Cruz Ramírez MD. Crohn's disease and cystic fibrosis: there is still a lot to learn. Rev Esp Enferm Dig. 2018;110(12):835-836.
Kim SH, Yang DH, Kim JS. Current Status of Interpretation of Small Bowel Capsule Endoscopy. Clin Endosc. 2018; 51(4):329-333.
Mitselos IV, Christodoulou DK. What defines quality in small bowel capsule endoscopy. Ann Transl Med. 2018; 6(13):260.
Chetcuti Zammit S, Sanders DS, Sidhu R. A comprehensive review on the utility of capsule endoscopy in coeliac disease: From computational analysis to the bedside. Comput Biol Med. 2018; 102:300-314.
Rokkas T, Papaxoinis K, Triantafyllou K, et al. Does purgative preparation infuence the diagnostic yield of small bowel video capsule endoscopy?: A meta-analysis. Am J Gastroenterol. 2009; 104:219–227.
Belsey J, Crosta C, Epstein O, et al. Meta-analysis: efficacy of small bowel preparation for small bowel video capsule endoscopy. Curr Med Res Opin. 2012; 28:1883–1890.
Hookey L, Louw J, Wiepjes M, et al. Lack of beneft of active preparation compared with a clear fluid-only diet in small-bowel visualization for video capsule endoscopy: results of a randomized, blinded, controlled trial. Gastrointest Endosc. 2017; 85:187–193.
Magalhães-Costa P, Carmo J, Bispo M, et al. Superiority of the split-dose peg regimen for small-bowel capsule endoscopy: a randomized controlled trial. J Clin Gastroenterol. 2016; 50:e65-70.
Di Nardo G, Calabrese C, Conti Nibali R, et al. Enteroscopy in children. United European Gastroenterol J. 2018; 6(7):961-969.
Esaki M, Matsumoto T, Ohmiya N, et al. Capsule endoscopy findings for the diagnosis of Crohn's disease: a nationwide case-control study. J Gastroenterol. 2019; 54(3):249-260.
Chetcuti Zammit S, McAlindon ME, Hale MF, et al. Small Bowel Ulcers on Capsule Endoscopy and Their Significance. Inflamm Bowel Dis. 2019; 25(5): e55.
Enns RA, Hookey L, Armstrong D, et al. Clinical Practice Guidelines for the Use of Video Capsule Endoscopy. Gastroenterology. 2017; 152(3):497-514.
Jawaid S, Marya N, Gondal B, et al. Lower Endoscopic Diagnostic Yields Observed in Non-hematemesis Gastrointestinal Bleeding Patients. Dig Dis Sci. 2018; 63(12):3448- 3456.
Sanchez-Mete L, Stigliano V. Update on small bowel surveillance in hereditary colorectal cancer syndromes. Tumori. 2019;105(1):12-21.