Otozomal Dominat Nokturnal Frontal Lob Epilepsisi
Özet
Uyku ile ilişkili hipermotor epilepsi (UHE), uykuda ani başlayıp kısa süren stereotipik, hipermotor veya distonik motor nöbetlerle karakterize nadir bir sendromdur. Genellikle genetik yatkınlığın rol oynadığı bu durum, klinik öykü ve video EEG ile tanı almaktadır. İlk tedavi seçeneği olarak sıklıkla karbamazepin tercih edilmekte olup, uyku bozuklukları ve psikojenik nöbetlerden dikkatle ayırt edilmesi gerekmektedir. Klinik seyir genellikle hayat boyu sürse de zamanla nöbetlerin şekli ve sıklığı değişebilmektedir.
Sleep-related hypermotor epilepsy (SHE) is a rare syndrome characterized by sudden, brief, stereotypic hypermotor or dystonic motor seizures occurring primarily during sleep. Often linked to genetic factors, diagnosis typically relies on clinical history supported by video EEG monitoring. Carbamazepine is the primary treatment choice, while careful differentiation from non-REM sleep disorders and psychogenic seizures is essential. Although the condition often persists throughout life, the nature and frequency of seizures may evolve over time.
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