Ani Bebek Ölüm Sendromu
Özet
Ani Bebek Ölüm Sendromu (ABÖS), ilk yaş içerisindeki bebeklerde kapsamlı incelemelere rağmen ölüm nedeni belirlenemeyen ani ve beklenmedik kayıpları tanımlamaktadır. Patogenezinde multifaktöryel nedenler ve uykuda uyarılma tepkisinin yetersizliği gibi fizyolojik bozukluklar ön plandadır. Risk faktörleri arasında yüzüstü uyku pozisyonu, anne sigara kullanımı ve uygun olmayan uyku ortamı yer almakta olup, 1 yaşına kadar bebeklerin sırtüstü yatırılması en önemli önleyici tedbirdir.
Sudden Infant Death Syndrome (SIDS) refers to the sudden, unexpected death of an infant under one year of age that remains unexplained even after a thorough investigation. Its pathogenesis is multifactorial, characterized by physiological deficiencies in autonomic control and impaired arousal responses during sleep. Major risk factors include prone sleeping position, maternal smoking, and unsafe sleep environments, with back sleeping until the age of one being the primary preventive measure.
Referanslar
Beckwith JB. The sudden infant death syndrome. Curr Probl Pediatr. 1973;3(8):1–36
World Health Organization. International Statistical Classification of Diseases and Related Health Problems, Ninth Revision. Geneva, Switzerland: World Health Organization; 1979
World Health Organization. International Statistical Classification of Diseases and Related Health Problems, Tenth Revision. Geneva, Switzerland: World Health Organization; 1992
Shapiro-Mendoza CK, Palusci VJ, Hoffman B, et al; AAP TASK FORCE ON SUDDEN INFANT DEATH SYNDROME, COUNCIL ON CHILD ABUSE AND NEGLECT, COUNCIL ON INJURY, VIOLENCE, AND POISON PREVENTION, SECTION ON CHILD DEATH REVIEW AND PREVENTION, NATIONAL ASSOCIATION OF MEDICAL EXAMINERS. Half Century Since SIDS: A Reappraisal of Terminology. Pediatrics. 2021 Oct;148(4):e2021053746.
TASK FORCE ON SUDDEN INFANT DEATH SYNDROME. SIDS and Other Sleep-Related Infant Deaths: Updated 2016 Recommendations for a Safe Infant Sleeping Environment. Pediatrics. 2016 Nov;138(5):e20162938.
Centers for Disease Control and Prevention (CDC). Sudden infant death syndrome--United States, 1983-1994. MMWR Morb Mortal Wkly Rep. 1996 Oct 11;45(40):859-63.
Willinger M, James LS, Catz C. Defining the sudden infant death syndrome (SIDS): deliberations of an expert panel convened by the National Institute of Child Health and Human Development. Pediatr Pathol. 1991 Sep-Oct;11(5):677-84.
Moon RY, Horne RS, Hauck FR. Sudden infant death syndrome. Lancet. 2007 Nov 3;370(9598):1578-87.
Trachtenberg FL, Haas EA, Kinney HC, Stanley C, Krous HF. Risk factor changes for sudden infant death syndrome after initiation of Back-to-Sleep campaign. Pediatrics. 2012 Apr;129(4):630-8.
Willinger M, Hoffman HJ, Hartford RB. Infant sleep position and risk for sudden infant death syndrome: report of meeting held January 13 and 14, 1994, National Institutes of Health, Bethesda, MD. Pediatrics. 1994 May;93(5):814-9.
American Academy of Pediatrics Task Force on Sudden Infant Death Syndrome. The changing concept of sudden infant death syndrome: diagnostic coding shifts, controversies regarding the sleeping environment, and new variables to consider in reducing risk. Pediatrics. 2005 Nov;116(5):1245-55
Mathews TJ, Menacker F, MacDorman MF. Infant mortality statistics from the 2001 period linked birth/infant death data set. Natl Vital Stat Rep. 2003 Sep 15;52(2):1-28.
Spinelli J, Collins-Praino L, Van Den Heuvel C, Byard RW. Evolution and significance of the triple risk model in sudden infant death syndrome. J Paediatr Child Health. 2017 Feb;53(2):112-115.
Filiano JJ, Kinney HC. A perspective on neuropathologic findings in victims of the sudden infant death syndrome: the triple-risk model. Biol Neonate. 1994;65(3-4):194-7.
Leach CE, Blair PS, Fleming PJ et al. Epidemiology of SIDS and explained sudden infant deaths. CESDI SUDI Research Group. Pediatrics 1999; 104: e43.
Mitchell EA, Krous HF. Sudden unexpected death in infancy: a historical perspective. J Paediatr Child Health. 2015 Jan;51(1):108-12. doi: 10.1111/jpc.12818.
Hakeem GF, Oddy L, Holcroft CA, Abenhaim HA. Incidence and determinants of sudden infant death syndrome: a population-based study on 37 million births. World J Pediatr. 2015 Feb;11(1):41-7.
Kelly DH, Golub H, Carley D, Shannon DC. Pneumograms in infants who subsequently died of sudden infant death syndrome. J Pediatr 1986; 109: 249–54.
Schechtman VL, Harper RM, Kluge KA, Wilson AJ, Hoffman HJ, Southall DP. Heart rate variation in normal infants and victims of the sudden infant death syndrome. Early Hum Dev 1989; 19: 167–81.
Schwartz PJ, Stramba-Badiale M, Segantini A, et al. Prolongation of the QT interval and the sudden infant death syndrome. N Engl J Med 1998; 338: 1709–14.
Kluge KA, Harper RM, Schechtman VL, Wilson AJ, Hoffman HJ, Southall DP. Spectral analysis assessment of respiratory sinus arrhythmia in normal infants and infants who subsequently died of sudden infant death syndrome. Pediatr Res 1988; 24: 677–82.
Byard RW. Possible mechanisms responsible for the sudden infant death syndrome. J. Paediatr. Child Health 1991; 27: 147–57.
Franco P, Verheulpen D, Valente F, et al. Autonomic responses to sighs in healthy infants and in victims of sudden infant death. Sleep Med 2003; 4: 569–77
Phillipson EA, Sullivan CC. Arousal: the forgotten response to respiratory stimuli. Am Rev Respir Dis 1978; 118: 807–09.
Horner RL. Autonomic consequences of arousal from sleep: mechanisms and implications. Sleep 1996; 19 (10 suppl): S193–95.
Bhat RY, Hannam S, Pressler R, Rafferty GF, Peacock JL, Greenough A. Effect of prone and supine position on sleep, apneas, and arousal in preterm infants. Pediatrics 2006; 118: 101–07.
Kahn A, Groswasser J, Sottiaux M, Rebuffat E, Franco P, Dramaix M. Prone or supine body position and sleep characteristics in infants. Pediatr 1993; 91: 1112–15.
Myers MM, Fifer WP, Schaeff er L, et al. Eff ects of sleeping position and time after feeding on the organization of sleep/wake states in prematurely born infants. Sleep 1998; 21: 343–49.
Franco P, Groswasser J, Sottiaux M, Broadfield E, Kahn A. Decreased cardiac responses to auditory stimulation during prone sleep. Pediatrics 1996; 97: 174–78.
Horne RS, Ferens D, Watts AM, et al. The prone sleeping position impairs arousability in term infants. J Pediatr 2001; 138: 811–16.
Franco P, Groswasser J, Hassid S, Lanquart JP, Scaillet S, Kahn A. Prenatal exposure to cigarette smoking is associated with a decrease in arousal in infants. J Pediatr 1999; 135: 34–38.
Tirosh E, Libon D, Bader D. The effect of maternal smoking during pregnancy on sleep respiratory and arousal patterns in neonates. J Perinatol 1996; 16: 435–38.
Horne RS, Ferens D, Watts AM, et al. Effects of maternal tobacco smoking, sleeping position, and sleep state on arousal in healthy term infants. Arch Dis Child Fetal Neonatal Ed 2002; 87: F100–05.
Sawnani H, Jackson T, Murphy T, Beckerman R, Simakajornboon N. The effect of maternal smoking on respiratory and arousal patterns in preterm infants during sleep. Am J Respir Crit Care Med 2004; 169: 733–38.
Ackerman MJ, Siu BL, Sturner WQ, et al. Postmortem molecular analysis of SCN5A defects in sudden infant death syndrome. JAMA 2001; 286: 2264–69.
Plant LD, Bowers PN, Liu Q, et al. A common cardiac sodium channel variant associated with sudden infant death in African Americans, SCN5A S1103Y. J Clin Invest 2006; 116: 430–35.
Hunt CE. Gene-environment interactions: implications for sudden unexpected deaths in infancy. Arch Dis Child 2005; 90: 48–53.
Tester DJ, Ackerman MJ. Sudden infant death syndrome: how significant are the cardiac channelopathies? Cardiovasc Res 2005; 67: 388–96.
Narita N, Narita M, Takashima S, Nakayama M, Nagai T, Okado N. Serotonin transporter gene variation is a risk factor for sudden infant death syndrome in the Japanese population. Pediatrics 2001; 107: 690–92
Weese-Mayer DE, Berry-Kravis EM, Zhou L, et al. Sudden infant death syndrome: case-control frequency diff erences at genes pertinent to early autonomic nervous system embryologic development. Pediatr Res 2004; 56: 391–95.
Korachi M, Pravica V, Barson AJ, Hutchinson IV, Drucker DB. Interleukin 10 genotype as a risk factor for sudden infant death syndrome: determination of IL–10 genotype from wax-embedded postmortem samples. FEMS Immunol Med Microbiol 2004; 42: 125–29
Ostfeld BM, Esposito L, Perl H, Hegyi T. Concurrent risks in sudden infant death syndrome. Pediatrics. 2010 Mar;125(3):447-53. doi: 10.1542/peds.2009-0038. Epub 2010 Feb 15.
Hauck FR, Herman SM, Donovan M, et al. Sleep environment and the risk of sudden infant death syndrome in an urban population: the Chicago Infant Mortality Study. Pediatrics. 2003; 111(5 pt 2):1207–1214
Li DK, Petitti DB, Willinger M, et al. Infant sleeping position and the risk of sudden infant death syndrome in California, 1997-2000. Am J Epidemiol. 2003;157(5):446–455
Blair PS, Fleming PJ, Smith IJ, et al; CESDI SUDI Research Group. Babies sleeping with parents: case-control study of factors infl uencing the risk of the sudden infant death syndrome. BMJ. 1999;319(7223):1457–1461
Fleming PJ, Blair PS, Bacon C, et al; Confidential Enquiry into Stillbirths and Deaths Regional Coordinators and Researchers. Environment of infants during sleep and risk of the sudden infant death syndrome: results of 1993-5 case-control study for confi dential inquiry into stillbirths and deaths in infancy. BMJ. 1996;313(7051):191–195
Carpenter RG, Irgens LM, Blair PS, et al. Sudden unexplained infant death in 20 regions in Europe: case control study. Lancet. 2004;363(9404):185–191
Malloy MH. Trends in postneonatal aspiration deaths and reclassification of sudden infant death syndrome: impact of the “Back to Sleep” program. Pediatrics. 2002;109(4):661–665
Tablizo MA, Jacinto P, Parsley D, Chen ML, Ramanathan R, Keens TG. Supine sleeping position does not cause clinical aspiration in neonates in hospital newborn nurseries. Arch Pediatr Adolesc Med. 2007;161(5):507–510
Vandenplas Y, Rudolph CD, Di Lorenzo C, Hassall E, Liptak G, Mazur L, Sondheimer J, Staiano A, Thomson M, Veereman-Wauters G, Wenzl TG, North American Society for Pediatric Gastroenterology Hepatology and Nutrition, European Society for Pediatric Gastroenterology Hepatology and Nutrition. Pediatric gastroesophageal reflux clinical practice guidelines: joint recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN). J Pediatr Gastroenterol Nutr. 2009 Oct;49(4):498-547
Tappin D, Ecob R, Brooke H. Bedsharing, roomsharing, and sudden infant death syndrome in Scotland: a case-control study. J Pediatr. 2005 Jul;147(1):32-7.