Fokal Kortikal Displazi ve Cerrahi Yaklaşım
Özet
Fokal kortikal displazi (FKD), dirençli çocukluk çağı epilepsilerinin en sık görülen gelişimsel nedenlerinden biridir ve genellikle MRG bulguları ile teşhis edilir. Hastalığın patolojisi, genetik ve çevresel faktörlerin kortikal gelişim üzerindeki olumsuz etkilerine dayanmakta olup, farklı sınıflandırma sistemleriyle tanımlanmaktadır. İlaç tedavisine dirençli olgularda, odak bölgenin nörolojik fonksiyonlara zarar vermeden rezeksiyonu veya nöromodülasyon teknikleri cerrahi seçenekler olarak değerlendirilmektedir. Tedavi başarısı büyük ölçüde FKD tipine ve patolojik alanın tam olarak çıkarılabilmesine bağlıdır.
Focal cortical dysplasia (FCD) is one of the most common developmental causes of refractory childhood epilepsy, typically identified through MRI findings. The pathology of the disease stems from the adverse effects of genetic and environmental factors on cortical development, and it is defined by various classification systems. In cases resistant to medication, resection of the focal area without compromising neurological function or the use of neuromodulation techniques are considered as surgical options. The success of treatment largely depends on the FCD type and the ability to completely resect the pathological area.
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