Saç Dökülmesi
Özet
Saç dökülmesi, bireylerin yaşam kalitesini ve duygusal iyilik halini olumsuz etkileyen, evrimsel süreçte sağlık ve doğurganlık göstergesi olarak kabul edilen fizyolojik bir durumdur. Saçın büyüme döngüsü anagen, katagen, telogen ve ekzojen fazlarından oluşmakta; genetik faktörler, hormonal değişimler, stres ve çeşitli sistemik hastalıklar bu döngüyü bozarak dökülmeye yol açmaktadır. Tanı aşamasında klinik öykü ve fizik muayenenin yanı sıra saç çekme testi ve trikoskopi gibi yöntemler kullanılırken, tedavide minoksidil ve finasterid gibi FDA onaylı ilaçların yanı sıra saç transplantasyonu ve PRP gibi modern cerrahi yaklaşımlar tercih edilmektedir.
Hair loss is a physiological condition that negatively impacts quality of life and emotional well-being, historically perceived as an indicator of health and fertility. The hair growth cycle consists of anagen, catagen, telogen, and exogen phases, which can be disrupted by genetic factors, hormonal shifts, stress, and systemic diseases, leading to various types of alopecia. Diagnosis relies on clinical history, physical examination, and techniques like the pull test or trichoscopy, while treatment options include FDA-approved medications such as minoxidil and finasteride, alongside modern surgical approaches like hair transplantation and PRP.
Referanslar
Erdoğan B. Anatomy and Physiology of hair. In: Kutlubay Z, Serdaroglu S (eds). Hair and scalp disorders. London: IntechOpen; 2017. doi: 10.5772/67269
Hoover E, Alhajj M, Flores JL. Physiology, hair. In: StatPearls[Internet]. Treasure Island (FL): StatPearls Publishing; 2022. https://www.ncbi.nlm.nih.gov/books/NBK499948 [Accessed: 19th January 2022].
Likhitkar M, Shakur AA, Bansal KK, et al. Alopecia-reason and possible treatments. MOJ Drug Design Development & Therapy. 2018;2(5):198‒208.
McElwee KJ, Sinclair R. Hair physiology and its disorders. Drug Discovery Today: Disease Mechanisms. 2008;5(2):e163-e171.
Dağ D. Erişkin Erkeklerde Görülen Kalıtsal Saç Dökülmesi Ile Elin 2. Ve 4. Parmak Oranları Arasındaki İlişki (tez). Sivas: Cumhuriyet Üniversitesi, 2017.
Haas N. Hair over the ages and in art-the culture, and social history of hair and its depiction in art. In: Blume-Peytavi U, Tosti A, Trüeb R (eds). Hair growth and disorders. Berlin: Springer, 2008. doi: 10.1007/978-3-540-46911-7_27
Frost P. Evolution of long head hair in humans. Advances in Anthropology. 2015;05:274-281.
Phillips TG, Slomiany WP, Allison R. Hair loss: common causes and treatment. American Family Physician. 2017;96(6):371-378.
Turkay A, Uzuncakmak TK, Engin B, et al. Alopesi Areata: güncel gözden geçirme. Dermatoz. 2020;11(4):39-51. doi: 10.4274/dermatoz.galenos.2021.88598
Alyoussef A. Comparative study of the online over-the-counter hair loss products. Journal of Dermatology Research and Therapy. 2020;6:77. doi: 10.23937/2469-5750/1510077
Rambwawasvika H. Alopecia types, current and future treatment. Journal of Dermatology & Cosmetology. 2021;5:93-99.
Tamashunas NL, Bergfeld WF. Male and female pattern hair loss: treatable and worth treating. Cleveland Clinic Journal of Medicine. 2021;88(3):173-182.
Bosnić Z, Šarić B, Vučić D, et al. Alopecia in preexisting autoimmune thyroid disease in family medicine practice: can hyperprolactinemia induce hair loss? A case report. Acta Dermatovenerologica Alpina, Pannonica et Adriatica. 2021;30(2):75-77.
Lin RL, Garibyan L, Kimball AB, et al. Systemic causes of hair loss. Annals of Medicine. 2016;48(6):393-402.
Yorulmaz A. Androgenetik alopesi. Çağdaş Tıp Dergisi. 2016;6(3):248-254. doi: 10.16899/ctd.45565
Łukasik A, Kozicka K, Kłosowicz A, et al. The role of family history and its influence on the onset time in female pattern hair loss. Postepy Dermatologii Alergologii. 2021;38(5):815-818.
Sattar F, Almas U, Ibrahim NA, et al. Efficacy of oral vitamin D(3) therapy in patients suffering from diffuse hair loss (telogen effluvium). Journal of Nutritional Science and Vitaminology. 2021;67(1):68-71.
Kayiran O, Cihandide E. Evolution of hair transplantation. Plastic and Aesthetic Research. 2018;5:9. doi: 10.20517/2347-9264.2017.86
Gentile P. The new regenerative and innovative strategies in hair loss. EClinicalMedicine. 2021;37:100995. doi: 10.1016/j.eclinm.2021.100995.
Talei B, Shauly O, Gould D. Platelet rich plasma hybridized adipose transplant (PHAT) for the treatment of hair loss: a case series. Aesthetic Plastic Surgery. 2021;45(6):2760-2767.
Bütünleyici Tedaviler Araştırma Derneği (BÜTAD). Aylık bülten Aralık 2019. [Online] https://www.butad.org/sites/other/butad/uploads/yayinlar/aralik-2019.pdf [Accessed: 20th January 2022].
Chan L, Cook DK. Female pattern hair loss. Australian Journal of General Practice. 2018;47(7):459-464.
Sharquie KE, Jabbar RI. COVID-19 infection is a major cause of acute telogen effluvium. Irish Journal of Medical Science. 2021:1-5. doi: 10.1007/s11845-021-02754-5.
