Unutkanlık

Yazarlar

Başak Korkmazer
https://orcid.org/0000-0003-2977-0693

Özet

Bellek sisteminin işleyişini ve unutkanlığın etiyolojisini detaylandıran bu metin, hafızayı duyusal, kısa süreli ve uzun süreli olmak üzere kategorize ederek farklı beyin bölgelerinin bu süreçlerdeki rollerini açıklamaktadır. Unutkanlığın Alzheimer, vitamin eksiklikleri ve metabolik bozukluklar gibi çok çeşitli nedenleri olduğu belirtilirken, tanı aşamasında Mini Mental Durum Ölçeği gibi testler ile laboratuvar incelemelerinin önemi vurgulanmaktadır. Tedavi yaklaşımı ise altta yatan nedeni yönetmeyi, ilaç kullanımını düzenlemeyi ve yaşam kalitesini artırmayı hedeflerken, birinci basamak hekimlerinin erken teşhisteki kritik rolüne dikkat çekmektedir.

 

This text details the functioning of the memory system and the etiology of forgetfulness, categorizing memory into sensory, short-term, and long-term while explaining the roles of different brain regions in these processes. It states that forgetfulness has various causes such as Alzheimer's, vitamin deficiencies, and metabolic disorders, emphasizing the importance of tests like the Mini-Mental State Examination and laboratory evaluations in the diagnosis. The treatment approach aims to manage the underlying cause, regulate medication, and improve quality of life, highlighting the critical role of primary care physicians in early detection.

Referanslar

Squire LR. Memory and brain systems: 1969-2009. J Neurosci. 2009;29(41):12711–6. Doi: 10.1523/JNEUROSCI.3575-09.2009

Sellal F. Les amnésies transitoires chez le sujet âgé. Psychol Neuropsychiatr Vieil [Internet]. 2006;4(1):31–8.

Jonker C, Geerlings M, Schmand B. Are memory complaints predictive for dementia? A review of clinical and population-based studies. Int J Geriatr Psychiatry. 2000;15(11983–91). Doi: 10.1002/1099-1166(200011)15:11

Perquin M, Diederich N, Pastore J, Lair ML, Stranges S, Vaillant M. Prevalence of Dementia and Cognitive Complaints in the Context of High Cognitive Reserve: A Population-Based Study. PLoS One. 2015;10(9):e0138818. Doi: 10.1371/journal.pone.0138818

Maternik M. Understanding of and misconceptions around monosymptomatic nocturnal enuresis: findings from patient and physician surveys. J Pediatr Urol. 2019;15(1):37.e1-37.e8. Doi: 10.1016/j.jpurol.2018.09.013

Matthews BR. Memory Dysfunction. Contin Lifelong Learn Neurol. 2015;21(3 Behavioral Neurology and Neuropsychiatry):613. Doi: 10.1212/01.CON.0000466656.59413.29

Binder JR, Desai RH. The neurobiology of semantic memory. Trends Cogn Sci. 2011;15(11):527–36. Doi: 10.1016/j.tics.2011.10.001.

Quam C, Wang A, Todd Maddox W, Golisch K, Lotto A. Procedural-Memory, Working-Memory, and Declarative-Memory Skills Are Each Associated With Dimensional Integration in Sound-Category Learning. Front Psychol. 2018;9(OCT). Doi: 10.3389/fpsyg.2018.01828.

Baddeley A. Working memory: looking back and looking forward. Nat Rev Neurosci. 2003;4(10):829–39. Doi: 10.1038/nrn1201.

Scimeca JM, Kiyonaga A, D’Esposito M. Reaffirming the Sensory Recruitment Account of Working Memory. Trends Cogn Sci. 2018;22(3):190–2. Doi: 10.1016/j.tics.2017.12.007

Chavant F, Favrelière S, Lafay-Chebassier C, Plazanet C, Pérault-Pochat MC. Memory disorders associated with consumption of drugs: updating through a case/noncase study in the French PharmacoVigilance Database. Br J Clin Pharmacol. 2011;72(6):898. Doi: 10.1111/j.1365-2125.2011.04009.x

Tripathi M, Vibha D. Reversible dementias. Indian J Psychiatry. 2009;51(Suppl1):S52.

Ghosh A. Endocrine, metabolic, nutritional, and toxic disorders leading to dementia. Ann Indian Acad Neurol. 2010;13(Suppl2):S63. Doi: 10.4103/0972-2327.74247

Cobb JL, D’Agostino RB, Wolf PA. Norms for the Mini-Mental State Examination. JAMA J Am Med Assoc. 1993:10;270(18):2178. Doi: 10.1001/jama.1993.03510180048021

Blessed G, Tomlinson BE, Roth M. The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects. Br J Psychiatry. 1968;114(512):797–811. Doi: 10.1192/bjp.114.512.797

Toledo JB, Bjerke M, Chen K, Rozycki M, Jack CR, Weiner MW, et al. Memory, executive, and multidomain subtle cognitive impairment: clinical and biomarker findings. Neurology. 2015;85(2):144–53. Doi: 10.1212/WNL.0000000000001738

Reas ET, Hagler DJ, White NS, Kuperman JM, Bartsch H, Cross K, et al. Sensitivity of restriction spectrum imaging to memory and neuropathology in Alzheimer’s disease. Alzheimers Res Ther. 2017;9(1). Doi: 10.1186/s13195-017-0281-7

Nelson AP, O’Connor MG. Mild cognitive impairment: a neuropsychological perspective. CNS Spectr. 2008;13(1):56–64. Doi: 10.1017/s1092852900016163

Ford AH, Almeida OP. Management of Depression in Patients with Dementia: Is Pharmacological Treatment Justified? Drugs Aging. 2017;34(2):89–95. Doi: 10.1007/s40266-016-0434-6

Grutzendler J, Morris JC. Cholinesterase inhibitors for Alzheimer’s disease. Drugs. 2001;61(1):41–52. Doi: 10.2165/00003495-200161010-00005

McShane R, Westby MJ, Roberts E, Minakaran N, Schneider L, Farrimond LE, et al. Memantine for dementia. Cochrane database Syst Rev. 2019;3(3):1–446. Doi: 10.1002/14651858.CD003154.pub6

Downs M, Turner S, Bryans M, Wilcock J, Keady J, Levin E, et al. Effectiveness of educational interventions in improving detection and management of dementia in primary care: cluster randomised controlled study. BMJ Br Med J. 2006;332(7543):692. Doi: 10.1136/bmj.332.7543.692

Gelecek

15 Ekim 2022

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