Dismenore
Özet
Dismenore, mensturasyon döneminde yaşanan ağrılı adet görme durumudur ve primer (nedeni belirsiz) veya sekonder (altta yatan patolojiye bağlı) olarak iki ana sınıfa ayrılır. Temelinde uterusun aşırı kasılmasına bağlı gelişen hipoksi ve prostaglandin artışının yattığı düşünülmektedir. Tedavide ağrıyı gidermek için ilk seçenek olarak steroid olmayan anti-inflamatuar ilaçlar ve hormonal kontraseptifler kullanılırken, sıcak uygulama, egzersiz ve TENS gibi ilaç dışı yöntemler de destekleyici olarak önerilmektedir.
Dysmenorrhea is defined as painful menstruation and is classified as primary (no pelvic pathology) or secondary (related to conditions like endometriosis). It is thought to be caused by excessive uterine contractions leading to hypoxia and increased prostaglandin levels during the menstrual cycle. Management primarily involves non-steroidal anti-inflammatory drugs and hormonal contraceptives, alongside non-pharmacological treatments like heat application, exercise, and TENS therapy.
Referanslar
De Sanctis V, Soliman A, Bernasconi S, Bianchin L, Bona G, Bozzola M, Buzi F, De Sanctis C, Tonini G, Rigon F, Perissinotto E. Primary Dysmenorrhea in Adolescents: Prevalence, Impact and Recent Knowledge. Pediatr Endocrinol Rev. 2015 Dec;13(2):512-20. PMID: 26841639.
Ju H, Jones M, Mishra G. The prevalence and risk factors of dysmenorrhea. Epidemiol Rev. 2014;36:104-13. doi: 10.1093/epirev/mxt009. Epub 2013 Nov 26. PMID: 24284871.
Mie Kazama, Keiko Maruyama, Kazutoshi Nakamura, Prevalence of Dysmenorrhea and Its Correlating Lifestyle Factors in Japanese Female Junior High School Students, The Tohoku Journal of Experimental Medicine, 2015, Volume 236, Issue 2, Pages 107-113, Released May 29,2015 https://doi.org/10.1620/tjem.236.107
Hertweck SP. Dysfunctional uterine bleeding. Obstet Gynecol Clin North Am. 1992 Mar;19(1):129-49. PMID: 1584538.
Osayande, Amimi S., and Suarna Mehulic. "Diagnosis and initial management of dysmenorrhea." American family physician 89.5 (2014): 341-346.
Latthe, Pallavi et al. “Factors predisposing women to chronic pelvic pain: systematic review.” BMJ (Clinical research ed.) vol. 332,7544 (2006): 749-55. doi:10.1136/bmj.38748.697465.55
Sundell G, Milsom I, Andersch B. Factors influencing the prevalence and severity of dysmenorrhoea in young women. Br J Obstet Gynaecol. 1990 Jul;97(7):588-94. doi: 10.1111/j.1471-0528.1990.tb02545.x. PMID: 2390501.
Klein, J R, and I F Litt. “Epidemiology of adolescent dysmenorrhea.” Pediatrics vol. 68,5 (1981): 661-4.
Dawood, M Yusoff. “Primary dysmenorrhea: advances in pathogenesis and management.” Obstetrics and gynecology vol. 108,2 (2006): 428-41. doi: 10.1097/01.AOG.0000230214.26638.0c
Lundström, V, and K Gréen. “Endogenous levels of prostaglandin F2alpha and its main metabolites in plasma and endometrium of normal and dysmenorrheic women.” American journal of obstetrics and gynecology vol. 130,6 (1978): 640-6. doi:10.1016/0002-9378(78)90320-4
Nigam, S., et al. "Increased concentrations of eicosanoids and platelet-activating factor in menstrual blood from women with primary dysmenorrhea." Eicosanoids 4.3 (1991): 137-141.
Altunyurt, Sabahattin et al. “Primary dysmenorrhea and uterine blood flow: a color Doppler study.” The Journal of reproductive medicine vol. 50,4 (2005): 251-5.
Dmitrović, R. “Transvaginal color Doppler study of uterine blood flow in primary dysmenorrhea.” Acta obstetricia et gynecologica Scandinavica vol. 79,12 (2000): 1112-6. doi:10.1034/j.1600-0412.2000.0790121112.x
Dawood, M. Yusoff. "Nonsteroidal anti-inflammatory drugs and changing attitudes toward dysmenorrhea." The American journal of medicine 84.5 (1988): 23-29.
French, Linda. "Dysmenorrhea in adolescents." Pediatric Drugs 10.1 (2008): 1-7.
Missmer SA, Hankinson SE, Spiegelman D, Barbieri RL, Marshall LM, Hunter DJ. Incidence of laparoscopically confirmed endometriosis by demographic, anthropometric, and lifestyle factors. Am J Epidemiol. 2004;160(8):784–796.
Chatman, Donald L. "Pelvic peritoneal defects and endometriosis: Allen-Masters syndrome revisited." Fertility and sterility 36.6 (1981): 751-756.
López-Liria, Remedios, et al. "Efficacy of physiotherapy treatment in primary dysmenorrhea: a systematic review and meta-analysis." International Journal of Environmental Research and Public Health 18.15 (2021): 7832.
Marjoribanks J, Ayeleke RO, Farquhar C, Proctor M. Nonsteroidal anti‐inflammatory drugs for dysmenorrhoea. Cochrane Database of Systematic Reviews 2015, Issue 7. Art. No.: CD001751.
Taylor HS, Pal L, Seli E. Speroff’s Clinical Gynecologic Endocrinology and Infertility Ninth Edition Chapter 14. Menstruation-Related Disorders p485-508
American College of Obstetricians and Gynecologists. ACOG practice bulletin no. 110: noncontraceptive uses of hormonal contraceptives. Obstet Gynecol. 2010;115(1):206–218.
Wong CL, Farquhar C, Roberts H, Proctor M. Oral contraceptive pill for primary dysmenorrhoea. Cochrane Database of Systematic Reviews 2009, Issue 4. Art. No.: CD002120.
Smith, Roger P., and Andrew M. Kaunitz. "Patient education: Painful menstrual periods (dysmenorrhea)(Beyond the Basics)." Obstetrics, Gynecology and Women's Health. Topic 2174 (2017).
Earl RA, Grivell RM. Nifedipine for primary dysmenorrhoea. Cochrane Database of Systematic Reviews 2021, Issue 12. Art. No.: CD012912.
Akin MD, Weingand KW, Hengehold DA, Goodale MB, Hinkle RT, Smith RP. Continuous low-level topical heat in the treatment of dysmenorrhea. Obstet Gynecol. 2001;97(3):343–349
Proctor M, Farquhar C, Stones W, He L, Zhu X, Brown J. Transcutaneous electrical nerve stimulation for primary dysmenorrhoea. Cochrane Database of Systematic Reviews 2002, Issue 1. Art. No.: CD002123.
Wilson ML, Murphy PA. Herbal and dietary therapies for primary and secondary dysmenorrhoea (Cochrane Review). In: The Cochrane Library, Issue 3, 2001. Oxford: Update Software
Pattanittum P, Kunyanone N, Brown J, Sangkomkamhang US, Barnes J, Seyfoddin V, Marjoribanks J. Dietary supplements for dysmenorrhoea. Cochrane Database of Systematic Reviews 2016, Issue 3. Art. No.: CD002124.
Armour M, Ee CC, Naidoo D, Ayati Z, Chalmers KJ, Steel KA, de Manincor MJ, Delshad E. Exercise for dysmenorrhoea. Cochrane Database of Systematic Reviews 2019, Issue 9. Art. No.: CD004142.
