Laparoskopik Prosedürlerde Anestezi Yönetimi
Özet
Laparoskopik cerrahide anestezi yönetimi, operasyonun getirdiği fizyolojik değişimlere uyum sağlamayı hedefleyen kapsamlı bir süreçtir. Bu teknik; daha az ağrı, hızlı iyileşme ve kısa hastanede kalış süresi gibi avantajlar sunsa da, karın içine verilen karbondioksit (CO₂) gazı (pnömoperitoneum) ve hastaya verilen cerrahi pozisyonlar ciddi patofizyolojik etkiler yaratır. Pnömoperitoneum; kardiyovasküler sistemde kalp debisinin azalmasına ve tansiyon değişikliklerine, solunum sisteminde ise akciğer kapasitesinin daralmasına ve hiperkapniye yol açabilir. Özellikle obez veya kardiyopulmoner hastalığı olan bireylerde bu riskler daha belirgindir. Anestezi yönetiminde altın standart, endotrakeal entübasyon eşliğinde uygulanan kontrollü genel anestezidir. Operasyon boyunca ETCO₂, EKG, tansiyon ve kas gevşemesi gibi parametreler titizlikle monitörize edilmelidir. Rejyonel anestezi bazı avantajlar sağlasa da, genellikle genel anestezi ile kombine edilerek postoperatif ağrıyı azaltmak amacıyla tercih edilir. Ameliyat sonrası dönemde ise bulantı ve kusma en sık görülen komplikasyonlardır; bu durumun önlenmesi için multimodal analjezi ve uygun antiemetik tedaviler uygulanır. Sonuç olarak laparoskopi, cerrah ve anestezistin yakın iş birliğini gerektiren dinamik bir süreçtir.
Anesthetic management in laparoscopic surgery is a comprehensive process aimed at adapting to the physiological changes brought about by the operation. While this technique offers advantages such as less pain, rapid recovery, and shorter hospital stays, the carbon dioxide (CO₂) gas insufflated into the abdomen (pneumoperitoneum) and the surgical positions given to the patient create significant pathophysiological effects. Pneumoperitoneum can lead to decreased cardiac output and blood pressure changes in the cardiovascular system, as well as narrowing of lung capacity and hypercapnia in the respiratory system. These risks are more pronounced, especially in obese patients or those with cardiopulmonary diseases. The gold standard in anesthesia management is controlled general anesthesia performed with endotracheal intubation. Parameters such as ETCO₂, ECG, blood pressure, and muscle relaxation must be meticulously monitored throughout the operation. Although regional anesthesia provides some benefits, it is generally preferred in combination with general anesthesia to reduce postoperative pain. In the postoperative period, nausea and vomiting are the most common complications; multimodal analgesia and appropriate antiemetic treatments are applied to prevent this. Consequently, laparoscopy is a dynamic process that requires close cooperation between the surgeon and the anesthesiologist.
Referanslar
Miyasaka Y, Nakamura M, Wakabayashi G. Pioneers in laparoscopic hepatobiliary-pancreatic surgery. J Hepatobiliary Pancreat Sci. 2018 Jan;25(1):109-111. doi: 10.1002/jhbp.506. PMID: 28963814.
Gerges FJ, Kanazi GE, Jabbour-Khoury SI. Anesthesia for laparoscopy: a review. J Clin Anesth. 2006 Feb;18(1):67-78. doi: 10.1016/j.jclinane.2005.01.013. PMID: 16517337.
Struthers AD, Cuschieri A: Cardiovascular consequences of laparoscopic surgery. Lancet 352:568, 1998.
Koivusalo AM, Lindgren L: Effects of carbon dioxide pneumoperitoneum for laparoscopic cholecystectomy. Acta Anaesthesiol Scand 44:834, 2000.
Joris JL. Anesthesia for laparoscopic surgery. In: RD Miller, Fleisher LA, Jones RA, Savarese JJ, Wiener-Kronish JP, Young WL., editors. Miller's Anesthesia. Philadelphia, PA: Churchill Livingstone; 2005. p. 2289. 6th ed.
Gutt CN, Oniu T, Mehrabi A, et al. Circulatory and respiratory complications of carbon dioxide insufflation. Dig Surg 2004;21(2): 95- 105.
Neudecker J, Sauerland S, Neugebauer E, et al. The European Association for Endoscopic Surgery clinical practice guideline on the pneumoperitoneum for laparoscopic surgery. Surg Endosc. 2002 Jul;16(7):1121-43. doi: 10.1007/s00464-001-9166-7. Epub 2001 May 20. PMID: 12015619.
Demiroluk S. Effects of intraperitoneal and extraperitoneal carbon dioxide insufflation on blood gases during the perioperative period. J Laparoendosc Adv Surg Tech A 2004;14(4):219 - 22.
Hirvonen EA, Poikolainen EO, Pääkkönen ME, et al. The adverse hemodynamic effects of anesthesia, head-up tilt, and carbon dioxide pneumoperitoneum during laparoscopic cholecystectomy. Surg Endosc. 2000 Mar;14(3):272-7. doi: 10.1007/s004640000038. PMID: 10741448.
Böhm B, Schwenk U,Junghans T (2000) Das pneumoperitoneum Springer-Verlag, Berlin, pp 42−46
Joris JL, Chiche JD, Canivet JL, et al. Hemodynamic changes induced by laparoscopy and their endocrine correlates: Effects of clonidine. J Am Coll Cardiol 32:1389, 1998
Harris SN, Ballantyne GH, Luther MA, et al. Alterations of cardiovascular performance during laparoscopiccolectomy: A combined hemodynamic and echocardiographic analysis. Anesth Analg 83:482, 1996.
Rauh R, Hemmerling TM, Rist M, et al. Influence of pneumoperitoneum and patient positioning on respiratory system compliance. J Clin Anesth 2001;13(5):361- 5.
Ružman T, Mraović B, Šimurina T, et al. Transcranial Cerebral Oxymetric Monitoring Reduces Brain Hypoxia in Obese and Elderly Patients Undergoing General Anesthesia for Laparoscopic Cholecystectomy. Surg Laparosc Endosc Percutan Tech. 2017 Aug;27(4):248-252. doi: 10.1097/SLE.0000000000000444. PMID: 28708768.
Sprung J, Whalley DG, Falcone T, et al. The impact of morbid obesity, pneumoperitoneum, and posture on respiratory system mechanics and oxygenation during laparoscopy. Anesth Analg. 2002;94:1345–1350.
Gipson CL, Johnson GA, Fisher R, et al. Changes in cerebral oximetry during peritoneal insufflation for laparoscopic procedures. J Minim Access Surg. 2006 Jun;2(2):67-72. doi: 10.4103/0972- 9941.26651. PMID: 21170237; PMCID: PMC2997275.
Demyttenaere S, Feldman LS, Fried GM. Effect of pneumoperitoneum on renal perfusion and function: a systematic review. Surg Endosc. 2007 Feb;21(2):152-60. doi: 10.1007/s00464-006-0250-x. Epub 2006 Dec 9. PMID: 17160650.
Nguyen NT, Perez RV, Fleming N, et al. Effect of prolonged pneumoperitoneum on intraoperative urine output during laparoscopic gastric bypass. J Am Coll Surg 2002;195:476–483.
Glantzounis GK, Tselepis AD, Tambaki AP, et al. Laparoscopic surgery-induced changes in oxidative stress markers in human plasma. Surg Endosc 2001;15:1315–1319.
Ozmen MM, Kessaf Aslar A, Besler HT, et al. Does splanchnic ischemia occur during laparoscopic cholecystectomy? Surg Endosc 2002;16:468–471.
H.C. Turgut, M. Arslan An overview of treatment options for postoperative nausea and vomiting after laparoscopic surgical procedures, Anaesth. Pain Intensive Care 20 (2016) 193–200
Salihoglu Z, Demiroluk S, Cakmakkaya S, et al. Influence of the patient positioning on respiratory mechanics during pneumoperitoneum. Middle East J Anesthesiol 2002;16(5):521 - 8.
Johnston RV, Lawson NW, Nealon WH: Lower extremity neuropathy after laparoscopic cholecystectomy. Anesthesiology 77:835, 1992.
Amornyotin S. Anesthetic Consideration for Laparoscopic Surgery. Int J Anesth Res, 2013, 1.1: 3-7.
Cunningham AJ, Turner J, Rosenbaum S, et al. Transoesophageal echocardiographic assessment of haemodynamic function during laparoscopic cholecystectomy. Br J Anaesth 70:621, 1993.
Recart A, Gasanova I, White PF, et al. The effect of cerebral monitoring on recovery after general anesthesia: a comparison of the auditory evoked potential and Bispectral Index devices with standard clinical practice. Anesth Analg 2003;97(6):1667 - 74.
Collins LM, Vaghadia H. Regional anesthesia for laparoscopy. Anesthesiol Clin North America 2001;19(1):43 - 55.
Haydon GH, Dillon J, Simpson KJ, et al. Hypoxemia during diagnostic laparoscopy: a prospective study. Gastrointest Endosc 1996;44(2):124 - 8.
Hasaniya NW, Zayed FF, Faiz H, et al. Preinsertion local anesthesia at the trocar site improves perioperative pain and decreases costs of laparoscopic cholecystec‐ tomy. Surgical Endoscopy 2001; 15(9): 962-964
Tolchard S, Davies R, Martindale S. Efficacy of the subcostal transversusabdominis plane block in laparoscopic cholecystectomy: comparison with conventional port-site infiltration. Journal of Anaesthesiology Clinical Pharmacology 2012; 28(3): 339-343.
Naja MZ, Ziade MF, Lonnqvist PA. General anesthesia combined with bilateral para‐ vertebral blockade (T5-6) vs. general anesthesia for laparoscopic cholecystectomy: a prospective, randomized clinical trial. European Journal of Anaesthesiology 2004; 21(6): 489-495.
Hayel G. Anaesthetic management of laparoscopic surgery, Eastern Mediterranean Health Journal, vol 4, issue 1, 1998, 185-8
Fujii Y. Management of postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy. Surgical Endoscopy 2011; 25(3): 691-695.
Wu SJ, Xiong XZ, Cheng TY, et al. Efficacy of ondansetronvs metoclo‐ pramide in prophylaxis of postoperative nausea and vomiting after laparoscopic cholecystectomy: a systematic review and meta-analysis. Hepatogastroenterology 2012; 59(119), Doi: 10.5754/hge11811