Göğüs Cerrahisinin Postoperatif Analjezisinde Bölgesel Teknikler
Özet
Göğüs cerrahisi sonrası görülen şiddetli akut ağrının yönetimi, hastaların iyileşme süreci ve komplikasyonların önlenmesi açısından kritiktir. Geleneksel olarak torasik epidural analjezi (TEA) altın standart kabul edilse de hipotansiyon ve üriner retansiyon gibi yan etkiler nedeniyle alternatif yöntemler öne çıkmaktadır. Özellikle ultrason (US) rehberliğinin gelişimi; torakal paravertebral blok (TPVB), erektör spina plane blok (ESPB), retrolaminar blok (RLB) ve serratus anterior plane blok (SAPB) gibi daha güvenli ve az invaziv tekniklerin kullanımını artırmıştır. TPVB, TEA ile benzer etkinlik gösterirken daha az yan etki profiline sahiptir. Yeni nesil fasyal plan bloklarından ESPB ve RLB, lokal anestetiğin paravertebral alana dolaylı yayılımı prensibiyle çalışarak teknik kolaylık ve güvenlik sağlar. Video yardımlı torakoskopik cerrahi (VATS) gibi modern prosedürlerde bu az invaziv yöntemler daha çok tercih edilmektedir. Sonuç olarak, US eşliğinde uygulanan bu bölgesel teknikler multimodal analjezinin ayrılmaz bir parçası haline gelmiştir. Ancak, her yöntemin etkinliğini tam olarak belirlemek için cerrahi prosedür ve hasta özellikleri göz önünde bulundurularak daha fazla klinik çalışmaya ihtiyaç duyulmaktadır.
Management of severe acute pain following thoracic surgery is critical for the recovery process and prevention of complications. While thoracic epidural analgesia (TEA) is traditionally considered the gold standard, alternative methods are emerging due to side effects like hypotension and urinary retention. Specifically, the advancement of ultrasound (US) guidance has increased the use of safer, less invasive techniques such as thoracic paravertebral block (TPVB), erector spinae plane block (ESPB), retrolaminar block (RLB), and serratus anterior plane block (SAPB). TPVB demonstrates similar efficacy to TEA but with a better side-effect profile. Next-generation facial plane blocks like ESPB and RLB provide technical ease and safety by working on the principle of indirect spread of local anesthetic to the paravertebral space. In modern procedures such as video-assisted thoracoscopic surgery (VATS), these less invasive methods are preferred. Consequently, these US-guided regional techniques have become an integral part of multimodal analgesia. However, more clinical studies considering surgical procedures and patient characteristics are needed to fully determine the effectiveness of each method.
Referanslar
Tamura T, Mori S, Mori A, et al. A randomized controlled trial comparing paravertebral block via the surgical field with thoracic epidural block using ropivacaine for post-thoracotomy pain relief. J Anesth. 2017 Apr;31(2):263-270. doi: 10.1007/s00540-017-2307-5.
Sentürk M, Ozcan PE, Talu GK, et al. The effects of three different analgesia techniques on long-term postthoracotomy pain. Anesth Analg. 2002 Jan;94(1):11-5, table of contents. doi: 10.1213/00000539-200201000-00003.
Zengin M, Baldemir R, Ülger G, et al. Comparison of thoracic epidural analgesia and thoracic paravertebral block in pain management after thoracotomy. Anatolian Curr Med J 2022; 4(1); 70-75. doi: 10.38053/acmj.1034690
Joshi GP, Bonnet F, Shah R, et al. A systematic review of randomized trials evaluating regional techniques for postthoracotomy analgesia. Anesth Analg. 2008 Sep;107(3):1026-40. doi: 10.1213/01.ane.0000333274.63501.ff.
Bottiger BA, Esper SA, Stafford-Smith M. Pain management strategies for thoracotomy and thoracic pain syndromes. Semin Cardiothorac Vasc Anesth. 2014 Mar;18(1):45-56. doi: 10.1177/1089253213514484.
Zengin M, Baldemir R, Ulger G, et al. Postoperative Analgesic Efficacy of Thoracic Paravertebral Block and Erector Spinae Plane Block Combination in Video-Assisted Thoracic Surgery. Cureus. 2021 Jun 12;13(6):e15614. doi: 10.7759/cureus.15614.
Romero A, Garcia JE, Joshi GP. The state of the art in preventing postthoracotomy pain. Semin Thorac Cardiovasc Surg. 2013 Summer;25(2):116-24. doi: 10.1053/j.semtcvs.2013.04.002.
Chin KJ, Perlas A, Chan V, et al. Ultrasound imaging facilitates spinal anesthesia in adults with difficult surface anatomic landmarks. Anesthesiology. 2011 Jul;115(1):94-101. doi: 10.1097/ALN.0b013e31821a8ad4.
Salman A, Arzola C, Tharmaratnam U, et al. Ultrasound imaging of the thoracic spine in paramedian sagittal oblique plane: the correlation between estimated and actual depth to the epidural space. Reg Anesth Pain Med. 2011 Nov-Dec;36(6):542-7. doi: 10.1097/AAP.0b013e31823217e7.
Kessler J, Moriggl B, Grau T. The use of ultrasound improves the accuracy of epidural needle placement in cadavers. Surg Radiol Anat. 2014 Sep;36(7):695-703. doi: 10.1007/s00276-013-1243-9.
Auyong DB, Hostetter L, Yuan SC, et al. Evaluation of Ultrasound-Assisted Thoracic Epidural Placement in Patients Undergoing Upper Abdominal and Thoracic Surgery: A Randomized, Double-Blind Study. Reg Anesth Pain Med. 2017 Mar/Apr;42(2):204-209. doi: 10.1097/AAP.0000000000000540.
Krediet AC, Moayeri N, van Geffen GJ, et al. Different Approaches to Ultrasound-guided Thoracic Paravertebral Block: An Illustrated Review. Anesthesiology. 2015 Aug;123(2):459-74. doi: 10.1097/ALN.0000000000000747.
Scarfe AJ, Schuhmann-Hingel S, Duncan JK, et al. Continuous paravertebral block for post-cardiothoracic surgery analgesia: a systematic review and meta-analysis. Eur J Cardiothorac Surg. 2016 Dec;50(6):1010-1018. doi: 10.1093/ejcts/ezw168.
Yeung JH, Gates S, Naidu BV, et al. Paravertebral block versus thoracic epidural for patients undergoing thoracotomy. Cochrane Database Syst Rev. 2016 Feb 21;2(2):CD009121. doi: 10.1002/14651858.CD009121.pub2.
Costache I, Sinclair J, Farrash FA, et al. Does paravertebral block require access to the paravertebral space? Anaesthesia. 2016 Jul;71(7):858-9. doi: 10.1111/anae.13527.
Voscopoulos C, Palaniappan D, Zeballos J, et al. The ultrasound-guided retrolaminar block. Can J Anaesth. 2013 Sep;60(9):888-95. doi: 10.1007/s12630-013-9983-x.
Zeballos JL, Voscopoulos C, Kapottos M, et al. Ultrasound-guided retrolaminar paravertebral block. Anaesthesia. 2013 Jun;68(6):649-51. doi: 10.1111/anae.12296.
Forero M, Adhikary SD, Lopez H, et al. The Erector Spinae Plane Block: A Novel Analgesic Technique in Thoracic Neuropathic Pain. Reg Anesth Pain Med. 2016 Sep-Oct;41(5):621-7. doi: 10.1097/AAP.0000000000000451.
Bryskin RB, Robie DK, Mansfield FM, et al. Introduction of a novel ultrasound-guided extrathoracic sub-paraspinal block for control of perioperative pain in Nuss procedure patients. J Pediatr Surg. 2017 Mar;52(3):484-491. doi: 10.1016/j.jpedsurg.2016.09.065.
Zengin M, Sazak H, Baldemir R, et al. The Effect of Erector Spinae Plane Block and Combined Deep and Superficial Serratus Anterior Plane Block on Acute Pain After Video-Assisted Thoracoscopic Surgery: A Randomized Controlled Study. J Cardiothorac Vasc Anesth. 2022 Feb 4:S1053-0770(22)00081-7. doi: 10.1053/j.jvca.2022.01.048.
Blanco R, Parras T, McDonnell JG, et al. Serratus plane block: a novel ultrasound-guided thoracic wall nerve block. Anaesthesia. 2013 Nov;68(11):1107-13. doi: 10.1111/anae.12344.
Blanco R. A reply. Anaesthesia. 2014 Oct;69(10):1173-4. doi: 10.1111/anae.12848.
Durant E, Dixon B, Luftig J, et al. Ultrasound-guided serratus plane block for ED rib fracture pain control. Am J Emerg Med. 2017 Jan;35(1):197.e3-197.e6. doi: 10.1016/j.ajem.2016.07.021.
Madabushi R, Tewari S, Gautam SK, et al. Serratus anterior plane block: a new analgesic technique for post-thoracotomy pain. Pain Physician. 2015 May-Jun;18(3):E421-4. PMID: 26000690.