Retensiyo Sekundinarum
Özet
Süt ineği işletmelerinde ekonomik sürdürülebilirliği olumsuz etkileyen en önemli reprodüktif ve metabolik hastalıklardan biri olan Retensiyo Sekundinarum, doğumdan sonraki 24 saat içerisinde yavru zarlarının (plasenta) kendiliğinden atılamaması durumu olarak tanımlanmaktadır. Fizyolojik olarak doğum sonrasındaki ilk 6 ila 12 saat içinde atılması gereken bu zarların kalması; fötomaternal yapışmayı sağlayan kotiledon-karunkul bağlantısının zamanında yıkımlanamamasından ve özellikle kollajenaz enzim aktivitesindeki yetersizliklerden kaynaklanmaktadır. Sürülerdeki görülme sıklığı %4-18 arasında değişmekle birlikte ikiz gebelikler, güç doğumlar, erken doğumlar ve beslenme hataları gibi faktörler bu insidansı önemli ölçüde artırmaktadır. Hastalık; süt veriminde azalmaya, metritis ve ketozis gibi puerperal hastalıklara yatkınlığa, servis periyodu ile doğum aralığının uzamasına ve dolayısıyla ciddi doğrudan ekonomik kayıplara yol açmaktadır. Tedavi yaklaşımında geleneksel olan elle kurtarma yöntemi endometrium hasarı ve enfeksiyon riskini artırdığı için günümüzde yerini büyük oranda hayvanın beden ısısı ile iştahının izlendiği kendi haline bırakma yöntemine bırakmıştır. Bunun yanı sıra sınırlı vakalarda hormon tedavileri veya umblikal artere kollajenaz enjeksiyonları uygulanabilse de en etkili strateji geçiş döneminde dengeli besleme, E vitamini ve selenyum takviyeleri ile koruyucu önlemler almaktır.
Retensiyo Sekundinarum, one of the most critical reproductive and metabolic diseases affecting economic sustainability in dairy cattle enterprises, is defined as the failure to expel fetal membranes (placenta) within 24 hours postpartum. The retention of these membranes, which should physiologically be expelled within the first 6 to 12 hours after calving, stems from the failure to timely breakdown the cotyledon-caruncle attachment that provides fetomaternal adhesion, particularly due to insufficiencies in collagenase enzyme activity. Although its incidence in herds varies between 4% and 18%, factors such as twin pregnancies, dystocia, premature births, and nutritional deficiencies significantly increase this rate. The disease leads to decreased milk yield, predisposition to puerperal diseases like metritis and ketosis, prolonged service period and calving intervals, and consequently severe direct economic losses. Since the traditional manual removal method in treatment increases the risk of endometrial damage and infection, it has largely been replaced today by the non-intervention method, where the animal's body temperature and feed intake are closely monitored. Additionally, although hormone therapies or collagenase injections into the umbilical artery can be applied in limited cases, the most effective strategy is to take prophylactic measures through balanced nutrition and vitamin E and selenium supplementation during the transition period.
Referanslar
Rajala P, Gröhn Y. Effects of dystocia, retained placenta, and metritis on milk yield in dairy cows. Journal of Dairy Science. 1998;81(12):3172-81.
Mahnani A, Sadeghi-Sefidmazgi A, Ansari-Mahyari S, et al. Assessing the consequences and economic impact of retained placenta in Holstein dairy cattle. Theriogenology. 2021;175:61-8.
Bello N, Stevenson J, Tempelman R. Invited review: Milk production and reproductive performance: Modern interdisciplinary insights into an enduring axiom. Journal of Dairy Science. 2012;95(10):5461-75.
LeBlanc SJ. Postpartum uterine disease and dairy herd reproductive performance: a review. The Veterinary Journal. 2008;176(1):102-14.
Drillich M, Reichert U, Mahlstedt M, et al. Comparison of two strategies for systemic antibiotic treatment of dairy cows with retained fetal membranes: preventive vs. selective treatment. Journal of Dairy Science. 2006;89(5):1502-8.
Gaafar H, Shamiah SM, Shitta A, et al. Some factors affecting on retained placenta and its effects on postpartum reproductive performance and milk production of Friesian cows. Slovak Journal of Animal Science. 2010;43(1):6-12.
Mahnani A, Sadeghi-Sefidmazgi A, Ansari-Mahyari S,et al. Farm and cow factors and their interactions on the incidence of retained placenta in holstein dairy cows. Theriogenology. 2021;159:87-97.
Han YK, Kim IH. Risk factors for retained placenta and the effect of retained placenta on the occurrence of postpartum diseases and subsequent reproductive performance in dairy cows. Journal of Veterinary Science. 2005;6(1):53-9.
Tucho TT, Ahmed WM. Economic and reproductive impacts of retained placenta in dairy cows. Journal of Reproduction and Infertility. 2017;8(1):18-27.
Grunert E. Etiology and pathogenesis of retained bovine placenta. In: Morrow DA (eds.) Current Therapy in Theriogenology. Philadelphia: WB Saunders; 1986. p. 237-242.
Eiler H. Retained placenta. In, Youngquist RS (Ed): Current Therapy in Large Animal Theriogenology. Philadelphia: WB Saunders; 1997. p. 340-348
Kumari S, Prasad S, Kumaresan A, et al. Risk factors and impact of retained fetal membranes on performance of dairy bovines reared under subtropical conditions. Tropical Animal Health and Production. 2015;47(2):285-90.
Kurtdede E, Kara E, Elifoğlu TB, et al. Evaluation of hepatokines, proinflammatory cytokines, oxidative stress and energy related metabolism analytes and hematological parameters in dairy cows with placental retention. Eurasian Journal of Veterinary Sciences. 2021;37(4):252 - 8.
Noakes D, Vermut J. Dystocia and other disorders associated with parturition. In: Noakes DE, Parkinson TJ, England GCW (eds.) Veterinary Reproduction and Obstetrics 9th ed. London: Saunders Elsevier; 2009. p. 207-305.
Bastan A. İneklerde Kuru, Geçiş ve Postpartum Dönem ile Yenidoğan Buzağı Yönetimi. Ankara: Neyir Matbaacılık; 2022.
Esslemont R, Kossaibati M. Incidence of production diseases and other health problems in a group of dairy herds in England. Veterinary Record. 1996;139(20):486-90.
Goff J. Major advances in our understanding of nutritional influences on bovine health. Journal of Dairy Science. 2006;89(4):1292-301.
Ghavi Hossein-Zadeh N, Ardalan M. Cow-specific risk factors for retained placenta, metritis and clinical mastitis in Holstein cows. Veterinary Research Communications. 2011;35(6):345-54.
Kimura K, Goff JP, Kehrli Jr ME, et al. Decreased neutrophil function as a cause of retained placenta in dairy cattle. Journal of Dairy Science. 2002;85(3):544-50.
Yazlık MO, Çolakoğlu HE, Pekcan M, et al. The evaluation of superoxide dismutase activity, neutrophil function, and metabolic profile in cows with retained placenta. Theriogenology. 2019;128:40-6.
Sheldon IM, Lewis GS, LeBlanc S, et al. Defining postpartum uterine disease in cattle. Theriogenology. 2006;65(8):1516-30.
Kossaibati M, Esslemont R. The costs of production diseases in dairy herds in England. The Veterinary Journal. 1997;154(1):41-51.
Martin J, Wilcox C, Moya J, et al. Effects of retained fetal membranes on milk yield and reproductive performance. Journal of Dairy Science. 1986;69(4):1166-8.
Fourichon C, Seegers H, Malher X. Effect of disease on reproduction in the dairy cow: a meta-analysis. Theriogenology. 2000;53(9):1729-59.
Gröhn Y, Rajala-Schultz P. Epidemiology of reproductive performance in dairy cows. Animal Reproduction Science. 2000;60:605-14.
Bar D, Ezra E. Effects of common calving diseases on milk production in high yielding dairy cows. Israel Journal of Veterinary Medicine. 2005;60(4):106.
Petit H. Feed intake, milk production and milk composition of dairy cows fed flaxseed. Canadian Journal of Animal Science. 2010;90(2):115-27.
Könyves L, Szenci O, Jurkovich V, et al. Risk assessment and consequences of retained placenta for uterine health, reproduction and milk yield in dairy cows. Acta Veterinaria Brno. 2009;78(1):163-72.
Beagley J, Whitman K, Baptiste K, et al. Physiology and treatment of retained fetal membranes in cattle. Journal of Veterinary Internal Medicine. 2010;24(2):261-8.
Heinonen M, Heinonen K. Retained placenta in cattle: the effect of treatment or nontreatment on puerperal diseases and subsequent fertility. Acta Veterinaria Scandinavica. 1989;30(4):425-9.